New York Ketamine Infusions — Manhattan, NYC
An independent directory profile of New York Ketamine Infusions' Lower Manhattan treatment center, including location details, depression treatments offered, patient access information and questions to consider before scheduling care.
Quick Answer: What is New York Ketamine Infusions in Manhattan?
New York Ketamine Infusions is a specialty treatment provider with a New York City clinic at 160 Broadway, 16th Floor, in Lower Manhattan. The provider offers IV ketamine therapy and SPRAVATO® treatment and describes care for depression, treatment-resistant depression and several other mental health conditions. Treatment eligibility is determined through individual clinical screening.
New York City Center at a Glance
These practical details are based on information currently published by New York Ketamine Infusions. Confirm scheduling, eligibility and coverage directly with the center before treatment.
New York, NY 10038
9:00 AM–7:00 PM
About the Manhattan Center
New York Ketamine Infusions serves patients from its Lower Manhattan clinic and a separate Long Island location in Melville. The provider's New York City service area includes Manhattan neighborhoods and nearby communities across New York City.
For people researching depression care, the important distinction is that this is a specialty center rather than a comprehensive directory of every depression treatment modality. Its website emphasizes ketamine infusion therapy and SPRAVATO®.
- Lower Manhattan treatment location
- IV ketamine therapy
- SPRAVATO® (esketamine) treatment
- Clinical screening before treatment
- SPRAVATO® insurance benefits verification for eligible patients
- Separate Melville, Long Island treatment location
How a Depression Treatment Plan Takes Shape
Treatment planning usually develops through evaluation, review of previous care, comparison of appropriate options and continued monitoring.
Clarify the diagnosis
Review symptoms, duration, medical history and whether another condition could be contributing.
Review past treatment
Document previous therapy, medications, doses, treatment duration, benefits and side effects.
Compare appropriate options
Discuss likely benefits, risks, practical requirements and alternatives—including whether specialty care is relevant.
Monitor and adjust
Track symptoms and daily functioning, then refine treatment based on response and tolerability.
Depression Treatments Featured at NYKI Manhattan
The center prominently offers two related but distinct treatments. Neither should be treated as interchangeable, and eligibility depends on clinical evaluation.
IV Ketamine Therapy
NYKI provides intravenous ketamine therapy for depression and other conditions it treats. Ketamine has a long-standing FDA-approved role as an anesthetic; its use for depression is off-label. NIMH-supported research has documented rapid antidepressant effects in some people with difficult-to-treat depression, while also emphasizing side effects and misuse concerns.
NYKI Ketamine InformationSPRAVATO® / Esketamine
SPRAVATO® is esketamine nasal spray. Current FDA labeling includes treatment-resistant depression in adults as monotherapy or with an oral antidepressant. It must be administered under required healthcare supervision and includes post-dose monitoring requirements.
NYKI SPRAVATO® InformationIV Ketamine vs. SPRAVATO® at a Glance
Both are associated with glutamatergic signaling, but their regulatory status, medication formulation, administration and coverage pathways differ.
| Feature | IV Ketamine | SPRAVATO® |
|---|---|---|
| Medication | Ketamine | Esketamine |
| Depression regulatory status | Used off-label for depression | FDA-approved for specific depressive indications |
| Administration | Intravenous infusion | Nasal spray administered under healthcare supervision |
| Monitoring | Clinical monitoring determined by the treating medical team | FDA labeling requires monitoring after administration; patients are assessed before discharge |
| Insurance | Coverage varies and may be limited for off-label ketamine treatment | May be covered for eligible patients depending on plan requirements, medical necessity and authorization |
Who Might Be Evaluated for Specialty Depression Treatment?
Depression treatment is not one-size-fits-all. NIMH notes that treatment commonly involves psychotherapy, medication or both, with other options considered when symptoms do not improve sufficiently. A specialty center may become relevant when a person and their treating clinicians are considering additional approaches after previous care.
For SPRAVATO®, FDA indications and safety requirements establish specific clinical parameters. For IV ketamine used for depression, the treatment is off-label and requires individualized medical judgment.
What the NYKI Intake and Treatment Process May Involve
NYKI states that its protocol begins with an intake conversation with a physician to determine whether ketamine may be appropriate. The exact process differs by treatment and individual clinical needs.
Initial Contact
Patients contact the center or submit a consultation request and provide initial information.
Clinical Screening
A clinician reviews relevant history and whether the requested treatment may be appropriate.
Access & Authorization
For SPRAVATO®, insurance benefits and authorization requirements may be reviewed when applicable.
Treatment & Monitoring
Eligible patients receive treatment in the clinical setting with treatment-specific monitoring and follow-up.
SPRAVATO® Insurance and Access
NYKI states that SPRAVATO® may be covered by commercial insurance, Medicare, Medicaid or other health plans for patients who meet clinical and plan-specific requirements. Coverage is not automatic: benefits, medical necessity, prior authorization and insurer rules can affect access.
The center also states that its team can help eligible patients review insurance information and understand authorization requirements before treatment.
NYKI Manhattan Location & New York City Access
The clinic is located at 160 Broadway in Lower Manhattan. NYKI describes its New York City location as serving Manhattan as well as patients traveling from nearby NYC communities.
New York Ketamine Infusions — NYC
160 Broadway, 16th Floor
New York, NY 10038
Phone: 917-261-7370
Treatment hours: 7 days a week, 9:00 AM–7:00 PM
Also Serving Long Island
NYKI operates a second location at 150 Broadhollow Rd, Suite 103, Melville, NY 11747. That center will have a separate DepressionTreatment.info profile so geographic and provider information remains organized by location.
Need immediate help?
If you or someone else is in immediate danger, call 911. For free, confidential mental health crisis support, call or text 988. A directory profile or routine treatment consultation is not a substitute for emergency or crisis care.
Authority Sources and References
Use independent clinical and regulatory sources alongside provider information when researching depression treatment.
National Institute of Mental Health
Overview of depression, psychotherapy, medication and other treatment approaches.
NIMH Depression Guide →U.S. Food & Drug Administration
Current SPRAVATO® prescribing information, approved indications, dosing, warnings and monitoring requirements.
FDA Prescribing Information →New York Ketamine Infusions
Primary provider source for location, hours, services, consultation process and insurance information described in this profile.
Provider Website →Frequently Asked Questions About New York Ketamine Infusions in Manhattan
Where is New York Ketamine Infusions located in Manhattan?
What depression treatments does NYKI Manhattan offer?
Is IV ketamine FDA-approved for depression?
Is SPRAVATO® FDA-approved for treatment-resistant depression?
Does NYKI accept insurance for SPRAVATO®?
Does NYKI also have a Long Island location?
How do I know whether ketamine or SPRAVATO® is appropriate for me?
Research the Center, Then Compare Your Options
Visit New York Ketamine Infusions for current provider information, or return to the Manhattan directory to compare this listing with additional centers as the directory expands.
Editorial disclosure: DepressionTreatment.info provides educational information and directory profiles. This profile is not a ranking, endorsement, diagnosis or treatment recommendation. Provider information is based in part on the provider's published materials and can change. Medical and regulatory statements should be confirmed with qualified clinicians and current official sources.
Getting to NYKI’s Manhattan Depression Treatment Center
New York Ketamine Infusions is located at 160 Broadway, 16th Floor, in Lower Manhattan. The treatment center is accessible from multiple New York City subway lines and is convenient for patients traveling from other parts of Manhattan, Brooklyn, Queens, and nearby New York City communities. Patients traveling for ketamine or SPRAVATO® treatment should confirm transportation requirements with the center before their appointment, as some treatments may affect the ability to drive afterward.